Increase in mutations by exposure of mammalian cells to ELF magnetic fields

Author

Miyakoshi, Junji ; Kitagawa, Kaori ; Yamagishi, Nobuyuki ; Shibata, Toru ; Takebe, Hiraku

Author_Institution

Dept. of Radiation Genetics, Kyoto Univ., Japan

Volume

5

fYear

1996

fDate

31 Oct-3 Nov 1996

Firstpage

1863

Abstract

Exposure to extremely low frequency magnetic fields (ELFMF) of 50 Hz and 400 mT induced mutations in the hypoxanthine-guanine phosphoribosyl transferase gene of human melanoma MeWo cells. The mutation frequency was enhanced both by increasing the exposure period and the induced current intensity. DNA replication error is suspected to cause the mutations produced by ELFMF exposure

Keywords

DNA; biological effects of fields; biomagnetism; cellular effects of radiation; genetics; magnetic field effects; 400 mT; 50 Hz; DNA replication error; ELF magnetic fields exposure effects; cellular radiation biology; human melanoma MeWo cells; hypoxanthine-guanine phosphoribosyl transferase gene; induced current intensity; mammalian cells; mutation frequency; mutations increase; Cancer; Cells (biology); DNA; Frequency; Genetic mutations; Geophysical measurement techniques; Ground penetrating radar; Humans; Magnetic fields; Malignant tumors;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE

Conference_Location

Amsterdam

Print_ISBN

0-7803-3811-1

Type

conf

DOI

10.1109/IEMBS.1996.646292

Filename

646292