Title :
Effect of homogeneous and inhomogeneous high magnetic fields on bacterial growth measured under a newly developed superconducting magnet biosystem
Author :
Shoda, Makoto ; Nakamura, Kazuhiro ; Okuno, Kazumasa ; Ano, Takashi
Author_Institution :
Res. Lab. of Resources Utilization, Tokyo Inst. of Technol., Yokohama, Japan
fDate :
31 Oct-3 Nov 1996
Abstract :
A new superconducting magnet biosystem (SBS) was developed which can provide 0.5 to 7 tesla (T) magnetic fields. The aerobic growth of a bacterium, Bacillus subtilis M1113 was investigated under homogeneous 7 T and inhomogeneous 5.2-6.1 T magnetic fields in SBS. In the stationary phase, the cell number under the magnetic field was about 2 times higher than that of a control, indicating that the high magnetic field inhibits the death rate of bacterial cells. A genetically transformed B. Subtilis M1113 (pC112) produced higher concentration of a lipopeptide antibiotic, surfactin, under a high magnetic field, reflecting higher cell numbers under a high magnetic field compared with that in the geomagnetic field
Keywords :
biological effects of fields; biological techniques; biomagnetism; cellular effects of radiation; magnetic field effects; superconducting magnets; 0.5 to 7 T; Bacillus subtilis M1113; aerobic growth; bacterial growth; cell number; cellular radiation biology; death rate inhibition; genetically transformed cells; homogeneous high magnetic fields; inhomogeneous high magnetic fields; lipopeptide antibiotic; stationary phase; superconducting magnet biosystem; surfactin; Antibiotics; Biological materials; Magnetic field measurement; Magnetic fields; Magnetic flux; Magnetic materials; Microorganisms; Superconducting magnets; Superconducting materials; Temperature control;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.646294
