High precision control of magnetically driven microtools for cell manipulations

This paper presents two innovative driving methodologies using magnetically driven microtools for precise cell manipulations and its automation systems. First, the magnetic analysis has been conducted to show the current MMT problem. Then, the new driving methodologies are introduced and backed up with FEM analysis and the experimental results. The positioning accuracy improves 3-10 times and the following response become 10 times higher against the driving linear stage. Using this methodology, the enucleation of oocytes is demonstrated to show the effectiveness of the method.