Application of an adaptive digital filter to resistive pulse detection: application to passage of erythrocytes through an oligopore filter

Author

Kehli, A. ; Senaoui, M. ; Larouk, A. ; Pautou, C. ; Boynard, M.

Author_Institution

Lab. de Biophys. Appl., Univ. Rene Descartes, Paris, France

Volume

5

fYear

1996

fDate

31 Oct-3 Nov 1996

Firstpage

1901

Abstract

In the present paper, the authors propose as an alternative to analog circuits, a numerical method based on an adaptive digital filter to detect each resistive pulse caused by the passage of individual red blood cells (RBC) through an oligopore filter. The cell transit analyser (CTA) was used. Application of the method shows that: 1. Baseline time variations of the signal are removed and 2. The signal to noise ratio (SNR) is increased. The method is well adapted to extract other pulse features to characterize red cells in term of their deformability

Keywords

adaptive filters; biological techniques; cellular transport; digital filters; haemorheology; adaptive digital filter; baseline time variations; cell deformability; cell transit analyser; erythrocytes passage; oligopore filter; pulse features extraction; red cells characterization; resistive pulse detection; signal to noise ratio; Adaptive filters; Biomembranes; Digital filters; Erbium; Frequency; Pulse circuits; Pulse measurements; Pulse shaping methods; Red blood cells; Signal to noise ratio;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE

Conference_Location

Amsterdam

Print_ISBN

0-7803-3811-1

Type

conf

DOI

10.1109/IEMBS.1996.646311

Filename

646311