Title :
Myocardial blood flow by PET: correction for spillover and partial volume
Author :
Bacharach, S.L. ; Bonow, R.O. ; Cuocolo, A. ; Perrone-Filardi, P. ; Voipio-Pulkki, L.-M. ; Carson, R.E. ; Frank, J.A. ; Maurea, S. ; Scheffknecht, B.
Author_Institution :
Nat. Inst. of Health, Bethesda, MD, USA
Abstract :
A method, based on the a bolus H215O blood flow measurement, which can correct for spillover and partial volume in position emission tomography (PET) is presented. The results of this method are compared, at least partially, to other methods, in particular the radiolabeled carbon monoxide method for predicting spillover and the use of high spatial resolution gated cardiac magnetic resonance imaging scans to predict partial volume (PV). The PV and spillover corrections derived from the 15O-water results can be used to correct for PV effects and spillover effects in the myocardial activity distribution of any other positron emitting isotope, for example 18F-deoxyglucose
Keywords :
biomedical measurement; cardiology; computerised tomography; flow measurement; haemodynamics; muscle; radioisotope scanning and imaging; 18F-deoxyglucose; H215O; gated cardiac magnetic resonance imaging scans; high spatial resolution scans; medical diagnostic imaging; partial volume; position emission tomography; positron emitting isotope; spillover; Blood flow; Carbon dioxide; Fluid flow measurement; Isotopes; Magnetic resonance imaging; Myocardium; Position measurement; Positron emission tomography; Spatial resolution; Volume measurement;
Conference_Titel :
Computers in Cardiology 1990, Proceedings.
Conference_Location :
Chicago, IL
Print_ISBN :
0-8186-2225-3
DOI :
10.1109/CIC.1990.144163
