Myocardial blood flow by PET: correction for spillover and partial volume

Author

Bacharach, S.L. ; Bonow, R.O. ; Cuocolo, A. ; Perrone-Filardi, P. ; Voipio-Pulkki, L.-M. ; Carson, R.E. ; Frank, J.A. ; Maurea, S. ; Scheffknecht, B.

Author_Institution

Nat. Inst. of Health, Bethesda, MD, USA

fYear

1990

fDate

23-26 Sep 1990

Firstpage

53

Lastpage

56

Abstract

A method, based on the a bolus H₂¹⁵O blood flow measurement, which can correct for spillover and partial volume in position emission tomography (PET) is presented. The results of this method are compared, at least partially, to other methods, in particular the radiolabeled carbon monoxide method for predicting spillover and the use of high spatial resolution gated cardiac magnetic resonance imaging scans to predict partial volume (PV). The PV and spillover corrections derived from the ¹⁵O-water results can be used to correct for PV effects and spillover effects in the myocardial activity distribution of any other positron emitting isotope, for example ¹⁸F-deoxyglucose

Keywords

biomedical measurement; cardiology; computerised tomography; flow measurement; haemodynamics; muscle; radioisotope scanning and imaging; ¹⁸F-deoxyglucose; H₂¹⁵O; gated cardiac magnetic resonance imaging scans; high spatial resolution scans; medical diagnostic imaging; partial volume; position emission tomography; positron emitting isotope; spillover; Blood flow; Carbon dioxide; Fluid flow measurement; Isotopes; Magnetic resonance imaging; Myocardium; Position measurement; Positron emission tomography; Spatial resolution; Volume measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 1990, Proceedings.

Conference_Location

Chicago, IL

Print_ISBN

0-8186-2225-3

Type

conf

DOI

10.1109/CIC.1990.144163

Filename

144163