Title :
Laser-induced in vivo oxyhemoglobin photodissociation and its application for local tissue oxygenation
Author_Institution :
B.I. Stepanov Inst. of Phys., Nat. Acad. of Sci. of Belarus, Minsk
fDate :
Sept. 29 2008-Oct. 4 2008
Abstract :
A novel method of local tissue oxygenation based on laser-induced in vivo photodissociation of oxyhemoglobin in cutaneous blood vessels is proposed. Dependents the value of additional oxygen extraction from oxyhemoglobin on the laser wavelength, irradiation time and the oxygen diffusion in different tissues are shown. The results of experimental study and computer modeling the kinetics of tissue oxygen distribution from blood plasma are presented. New laser-optical technology of local tissue oxygenation and elimination of hypoxia at irradiation zone is proposed. Different aspects of biomedical applications of the proposed new technology for elimination of local tissue hypoxia are discussed.
Keywords :
bio-optics; biological tissues; blood vessels; photodissociation; biomedical applications; blood plasma; blood vessels; hypoxia elimination; laser-optical technology; local tissue oxygenation; oxygen extraction; oxyhemoglobin photodissociation; tissue oxygen distribution; Application software; Biomedical computing; Blood vessels; Distributed computing; In vivo; Kinetic theory; Laser beam cutting; Laser modes; Plasma applications; Plasma waves; hypoxia; laser therapy; oxyhemoglobin; photodissociation; tissue oxygenation;
Conference_Titel :
Advanced Optoelectronics and Lasers, 2008. CAOL 2008. 4th International Conference on
Conference_Location :
Crimea
Print_ISBN :
978-1-4244-1973-9
Electronic_ISBN :
978-1-4244-1974-6
DOI :
10.1109/CAOL.2008.4671859
