Superresolution optical endoscopy imaging

Author

Gu, Min

Author_Institution

Swinburne Univ. of Technol., Hawthorn, VIC, Australia

fYear

2011

fDate

3-4 Dec. 2011

Firstpage

1

Lastpage

1

Abstract

The integration of femtosecond laser beams and optical microscopy has led to the invention of nonlinear optical microscopy which provides a revolutionary tool for three-dimensional (3D) imaging through thick tissue media. The recent development of fibre optics including photonic crystal fibre and its application into this new microscopy method has facilitated the emerging of nonlinear optical endoscopy for in vivo diagnosis and therapeutic studies. In this paper we present our recent cutting-edge progress on functional handheld fibre-optical nonlinear endoscopy and its application as a minimal invasive method for simultaneous diagnoses and treatment of cancer cells using transferrin-conjugated gold nanorods that are specifically labelled to cancer cells. In particular, we will report on a novel nonlinear optical endoscope using laser beams at two wavelengths for 3D superresolution imaging.

Keywords

biomedical optical imaging; cancer; cellular biophysics; endoscopes; gold; nanomedicine; nanorods; nonlinear optics; optical fibres; patient diagnosis; patient treatment; 3D superresolution imaging; cancer cell; functional handheld fibre-optical nonlinear endoscopy; laser beams; minimal invasive method; patient diagnosis; patient treatment; superresolution optical endoscopy imaging; transferrin-conjugated gold nanorod; Fiber nonlinear optics; Nonlinear optical devices; Optical fibers; Optical imaging; Ultrafast optics;

fLanguage

English

Publisher

ieee

Conference_Titel

Functional Optical Imaging (FOI), 2011

Conference_Location

Ningbo

Print_ISBN

978-1-4673-0452-8

Type

conf

DOI

10.1109/FOI.2011.6154826

Filename

6154826