Properties of the spatial distribution of repolarization time in atrial tissue

Author

Kay, M.W. ; Bayly, PV ; Schuessler, RB

Author_Institution

Dept. of Biomed. Eng., Washington Univ., St. Louis, MO, USA

Volume

1

fYear

1997

fDate

30 Oct-2 Nov 1997

Firstpage

355

Abstract

The spatial distribution of repolarization time in canine right atria was estimated from monophasic action potentials (MAPs) and characterized statistically. MAP waveforms were collected from 76 sites within the right atrium of 11 dogs under control conditions and with perfusion of 0.5 and 1.0 μM acetylcholine (ACH) solutions. The 90% action potential duration (APD90) was estimated automatically from MAP waveforms. Spatial resolution was investigated in two preparations by comparing APD90 fields generated using 76 data points to APD90 fields generated using 250 data points. The spatial mean of APD90, spatial standard deviation of APD90, mean gradient, and standard deviation of gradient were all found to be significantly different between the control and ACH preparations. ACH did not appear to increase the spatial randomness of APD90, as measured by estimates of correlation length and the effective wavelength of the APD90 field

Keywords

electrocardiography; medical signal processing; statistical analysis; APD90 field; ECG statistical characterization; acetylcholine solution; atrial tissue; canine right atria; correlation length; effective wavelength; monophasic action potentials; repolarization time spatial distribution; spatial randomness; spatial resolution; Biomedical engineering; Cardiology; Dogs; Drives; Length measurement; Mechanical engineering; Myocardium; Spatial resolution; Surgery; Wavelength measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE

Conference_Location

Chicago, IL

ISSN

1094-687X

Print_ISBN

0-7803-4262-3

Type

conf

DOI

10.1109/IEMBS.1997.754549

Filename

754549