Title :
Effect of extracorporeal shockwave therapy on nanostructural and property responses of the Achilles tendinitis rat model
Author :
Choi, Samjin ; Lee, Gi-Ja ; Lee, Sunghoon ; Cheong, Youjin ; Kwon, Eri ; Cho, Hyunjong ; Chon, Jinmann ; Yoo, Seung Don ; Park, Hun-Kuk
Author_Institution :
Department of Biomedical Engineering & Healthcare Industry Research Institute, College of Medicine, Kyung Hee University, Seoul 130-701 Republic of Korea
Abstract :
Extracorporeal shockwave (ESW) therapy is popular in the treatment of musculoskeletal injuries, but the mechanism by which ESW therapy might have an effect on a tendon injury is unknown. Therefore, this study examined the effects of ESW therapy on the progressive changes in the nanostructure and adhesion force of collagen fibrils of a rat Achilles tendinitis model induced by collagenase, using atomic force microscopy. The nanostructural progressive changes in morphology including the fibril diameter and D-periodicity, and properties such as the fibril adhesion force in each healing phase, were investigated over a 9-week period after injecting collagenase. The injured collagen network structures with the physical ESW therapy were returned to a well-aligned normal collagen network nanostructure. These results suggest that physical ESW therapy may promote the healing response to Achilles tendinitis.
Keywords :
In vivo; Medical treatment; Tendons;
Conference_Titel :
Nanotechnology Materials and Devices Conference (NMDC), 2011 IEEE
Conference_Location :
Jeju
Print_ISBN :
978-1-4577-2139-7
DOI :
10.1109/NMDC.2011.6155395
