Title :
Electrical stimulation of the small intestine in dogs
Author :
Lin, XM ; Peters, LJ ; Zhang, M. ; Qian, LW ; Ren, J. ; Hayes, J. ; Chen, JDZ
Author_Institution :
Thomas N. Lynn Inst. for Healthcare Res., Oklahoma City, OK, USA
fDate :
30 Oct-2 Nov 1997
Abstract :
The aim of this study was to investigate the effect of electrical stimulation of small intestine in dogs. Five healthy dogs were selected in this study. Four pairs of bipolar recording electrodes were implanted on the serosal surface of the duodenum at an interval of 5 cm. Several pacing parameters were chosen to evaluate the effect of electrical stimulation. The optimal pacing parameters for entrainment were found as: pacing pulse amplitude was 4 mA, width was 160 ms, frequency was 10% higher than the intrinsic frequency (IF). Effects of changing pacing pulse width, frequency and amplitude were also analyzed. The authors found that appropriate electrical stimulation of the small intestine could entrain intestinal myoelectrical activity
Keywords :
bioelectric phenomena; biological organs; 160 ms; 4 mA; 5 cm; bipolar recording electrodes; dogs; duodenum; electrical stimulation; healthy dogs; implanted electrodes; intestinal myoelectrical activity entrainment; intrinsic frequency; pacing parameters; pacing pulse amplitude; pacing pulse frequency; small intestine electrical stimulation; Cities and towns; Dogs; Electrical stimulation; Electrodes; Frequency; Heart; Humans; Intestines; Space vector pulse width modulation; Wires;
Conference_Titel :
Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
Print_ISBN :
0-7803-4262-3
DOI :
10.1109/IEMBS.1997.757078
