An image computing system for the estimation and reconstruction of diffuse volume of an anti-cancer drug in liver tumours

Author

Ip, Horace H S ; Lam, Stephen W C ; Arnold, M.M. ; Kreel, Louis

Author_Institution

Dept. of Comput. Sci., City Polytech. of Hong Kong, Hong Kong

fYear

1992

fDate

14-17 Jun 1992

Firstpage

391

Lastpage

397

Abstract

Presents a medical image computing system which has been designed to extract and analyze quantitative information from a spatial sequence of CT (computed tomography) images. In particular, it has been applied to the quantitation and 3D reconstruction of the diffuse pattern of a radio-opaque anti-cancer drug, lipiodol-doxorubicin, in hepatocellular carcinoma. The PC-based system computes quantitative measures which can be used to assess the effectiveness of the chemotherapeutic treatment and to study the histology of the tumour. The system can provide a visualization of the tumour volume and quantification of drug absorption using 3D surface reconstruction and graphics techniques

Keywords

computerised tomography; image reconstruction; liver; medical image processing; microcomputer applications; patient treatment; 3D surface reconstruction; PC-based system; anti-cancer drug; chemotherapeutic treatment; computed tomography; diffuse pattern reconstruction; diffuse volume estimation; drug absorption; graphics techniques; hepatocellular carcinoma; histology; lipiodol-doxorubicin; liver tumours; medical image computing system; quantitative measures; spatial image sequence; Biomedical imaging; Computed tomography; Data mining; Drugs; Image analysis; Image reconstruction; Image sequence analysis; Information analysis; Tumors; Visualization;

fLanguage

English

Publisher

ieee

Conference_Titel

Computer-Based Medical Systems, 1992. Proceedings., Fifth Annual IEEE Symposium on

Conference_Location

Durham, NC

Print_ISBN

0-8186-2742-5

Type

conf

DOI

10.1109/CBMS.1992.244924

Filename

244924