Title :
FT-IR chemical imaging of biomineralized tissues using a mercury-cadmium-telluride focal-plane array detector
Author :
Marcott, Curtis ; Reeder, Robert C. ; Paschalis, E.P. ; Boskey, Adele L. ; Mendelsohn, Richard
Author_Institution :
Miami Valley Labs., Procter & Gamble Co., Cincinnati, OH, USA
fDate :
30 Oct-2 Nov 1997
Abstract :
A 64×64 mercury-cadmium-telluride (MCT) focal-plane array detector attached to an FT-IR microscope was used to spectroscopically image 5-μm slices of human bone tissue in the fingerprint region of the infrared spectrum. The protein, carbonate, and phosphate concentrations change as function of distance from an osteon. Changes in the phosphate IR band shapes also occur, suggesting a spatial dependence to the biomineralization process
Keywords :
biochemistry; biological tissues; biomedical imaging; focal planes; infrared detectors; optical arrays; orthopaedics; 5 mum; FT-IR chemical imaging; biomineralized tissues; carbonate concentration; distance from osteon; fingerprint region; medical instrumentation; mercury-cadmium-telluride focal-plane array detector; phosphate IR band shapes change; phosphate concentration; protein concentration; spatial dependence; spectroscopic imaging; Bone tissue; Chemicals; Fingerprint recognition; Humans; Infrared detectors; Infrared imaging; Microscopy; Optical imaging; Sensor arrays; Spectroscopy;
Conference_Titel :
Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
Print_ISBN :
0-7803-4262-3
DOI :
10.1109/IEMBS.1997.757724
