Title :
Bioprocess automation using new online sensors
Author :
Jiang, Junfeng ; Fan, Shunjie ; Kong, Bing ; Cai, Haoyuan ; Guo, Min ; Zhuo, Vue
Author_Institution :
Corp. Technol., Siemens Ltd., China, Beijing, China
Abstract :
An automation system for bioprocess monitoring and control, based on the distributed control system SIMATIC PCS7 and new online sensors, is introduced. The system realizes on-line monitoring of O2 and CO2 concentrations in the exhaust gas, cell density and size during fermentation processes by new instruments. Different fermentation phases can be clearly identified using the newly developed online sensor, which is ideal for the implementation of advanced process control strategies. Instrumentation, automation, and experimental results are presented to show the effectiveness of the control system.
Keywords :
biotechnology; chemical sensors; computerised monitoring; distributed control; fermentation; process control; process monitoring; CO2; O2; SIMATIC PCS7; bioprocess automation system; bioprocess control; bioprocess monitoring; cell density; distributed control system; exhaust gas; fermentation processes; online monitoring; online sensors; Automatic control; Automation; Biosensors; Control systems; Distributed control; Instruments; Monitoring; Programmable control; Sensor systems; Temperature control; Bioprocess; Distributed Control System (DCS); fermentation; online sensor;
Conference_Titel :
Mechatronics and Automation, 2009. ICMA 2009. International Conference on
Conference_Location :
Changchun
Print_ISBN :
978-1-4244-2692-8
Electronic_ISBN :
978-1-4244-2693-5
DOI :
10.1109/ICMA.2009.5246326
