A frequency-shift readout system for FPW allergy biosensor

Author

Hsu, Chia-Hao ; Lin, Yain-Reu ; Tsai, Yue-Da ; Chen, Yun-Chi ; Wang, Chua-Chin

Author_Institution

Dept. of Electr. Eng., Nat. Sun Yat-Sen Univ., Kaohsiung, Taiwan

fYear

2011

fDate

2-4 May 2011

Firstpage

1

Lastpage

4

Abstract

In this paper, an IgE antigen concentration measurement system using a frequency-shift readout method for a two-port FPW (flexural plate-wave) allergy biosensor is presented. The proposed frequency-shift readout method adopts a peak detecting scheme to detect the resonant frequency. A linear frequency generator, a pair of peak detectors, two registers, and an subtractor are only needed in our system. According to the specification of the FPW allergy biosensor, the frequency sweep range is limited in 2 MHz to 10 MHz. The sensitivity of the peak detector is 0.8 mV. The proposed frequency-shift readout circuit is verified on silicon by using a standard 0.18 μm CMOS technology. The maximal power consumption is 12.94 mW@0.1 MHz clock given by HSPICE simulations.

Keywords

CMOS integrated circuits; SPICE; biosensors; readout electronics; CMOS technology; FPW allergy biosensor; HSPICE simulations; IgE antigen concentration measurement system; flexural plate-wave; frequency-shift readout system; Biological system modeling; Biosensors; Detectors; Immune system; Oscillators; Registers; Resonant frequency; FPW; IgE antigen; frequency-shift readout circuit; peak detection; resonant frequency;

fLanguage

English

Publisher

ieee

Conference_Titel

IC Design & Technology (ICICDT), 2011 IEEE International Conference on

Conference_Location

Kaohsiung

ISSN

Pending

Print_ISBN

978-1-4244-9019-6

Type

conf

DOI

10.1109/ICICDT.2011.5783241

Filename

5783241