Title :
Surface Hydrophilic Polyurea Film for PMMA Blood Analysis Chip Realized by Vacuum Ultraviolet Light Irradiation
Author :
Shinohara, H. ; Takahashi, Y. ; Nishi, T. ; Uemura, K. ; Takahashi, C. ; Mizuno, J. ; Shoji, S.
Author_Institution :
Waseda Univ., Tokyo
Abstract :
A novel hydrophilic method of the polyurea film surface at room temperature was developed using vacuum ultraviolet (VUV) light 172 nm in wavelength. The treated film has highly hydrophilic surface for long time (~ 2 months). Hydrophilic surface is stable and is kept even after very hard condition of ultrasonic cleaning in de-ionized water. The polyurea film was applied for PMMA (polymethylmethacrylate) blood analysis chip. The performance of the surface treatment was evaluated by actual human blood measurements. The new chip can reduce the adhesion of platelets and white blood cells, even after ultrasonic cleaning in surfactant induced water. This result indicates that this chip can be reused after washing.
Keywords :
adhesion; bioMEMS; biomedical measurement; blood; cellular biophysics; lab-on-a-chip; optical films; optical polymers; polymer films; ultrasonic cleaning; ultraviolet radiation effects; PMMA blood analysis chip; de-ionized water; human blood measuremen; hydrophilic polyurea film surface; microchannel array; platelet adhesion; polymethylmethacrylate; surface treatment; surfactant induced water; temperature 293 K to 298 K; ultrasonic cleaning; vacuum ultraviolet light irradiation; wavelength 172 nm; white blood adhesion; Adhesives; Anthropometry; Blood; Cleaning; Humans; Semiconductor device measurement; Surface treatment; Surface waves; Temperature; Ultrasonic variables measurement; Blood Analysis Chip; Poly-Methylmethacrylate; Polyurea Film; Vacuum Ultraviolet Light;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International
Conference_Location :
Lyon
Print_ISBN :
1-4244-0842-3
Electronic_ISBN :
1-4244-0842-3
DOI :
10.1109/SENSOR.2007.4300126
