Title :
Hydrolyticmicroneedles as Transdermal Drug Delivery System
Author :
Miyano, T. ; Miyachi, T. ; Okanishi, T. ; Todo, H. ; Sugibayashi, K. ; Uemura, T. ; Takano, N. ; Konishi, S.
Author_Institution :
Ritsumeikan Univ., Kusastu
Abstract :
We developed hydrolytic microneedles as a transdermal drug delivery system to overcome the shortcomings of existing microneedle-systems: long-term stay of broken needles in the skin and high cost for safe disposal of used needles. The present microneedles spontaneously dissolve by hydrolysis in human skin as well as in the (boiled) water. We verified their basic utility through experiments.
Keywords :
bioMEMS; biomedical equipment; drug delivery systems; needles; skin; MEMS; human skin; hydrolytic microneedles; microfabrication; transdermal drug delivery system; Costs; Drug delivery; Epidermis; Fabrication; Humans; Mice; Needles; Pharmaceutical technology; Sensor arrays; Skin; Bio-degradable; Drug delivery system; Hydrolytic; Microneedle;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International
Conference_Location :
Lyon
Print_ISBN :
1-4244-0842-3
Electronic_ISBN :
1-4244-0842-3
DOI :
10.1109/SENSOR.2007.4300141
