A feedback analysis of heart rate fluctuations related to blood pressure change: effect of autonomic blockade

Author

Mizuta, Hirohisa ; Takeuchi, Isao ; Tsuda, Osamu ; Yana, Kazuo

Author_Institution

Dept. of Electr. Inf., Hosei Univ., Tokyo, Japan

Volume

5

fYear

1997

fDate

1997

Firstpage

2184

Abstract

This paper describes the method of relating changes in blood pressure to the heart rate fluctuations. A linear signal generation model with a feedback loop has been introduced and bivariate autoregressive model is applied for the analysis. Computer simulation was carried out to see if the transfer characteristics in both directions could be estimated accurately under the circumstance where both heart rate and blood pressure have a common exogenous source of fluctuations with 1/f spectral pattern. Then the method was applied to the data from 14 male subjects aged from 19 to 38. It was concluded that the parasympathetic blockade abolishes the impulse response of the heart rate fluctuations to the change in blood pressure

Keywords

autoregressive processes; biocontrol; cardiovascular system; fluctuations; haemodynamics; neurophysiology; parameter estimation; physiological models; transient response; 1/f spectral pattern; autonomic blockade; bivariate autoregressive model; blood pressure change; computer simulation; exogenous source of fluctuations; feedback analysis; feedback loop; heart rate fluctuations; impulse response; linear signal generation model; neural control; parameter estimation accuracy; parasympathetic blockade; system identification; transfer characteristics; Aging; Blood pressure; Character generation; Computer simulation; Feeds; Fluctuations; Heart rate; Heart rate variability; Signal analysis; Signal generators;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE

Conference_Location

Chicago, IL

ISSN

1094-687X

Print_ISBN

0-7803-4262-3

Type

conf

DOI

10.1109/IEMBS.1997.758789

Filename

758789