Title :
Simultaneous Dielectrophoretic Separation and Impedimetric Detection of Microbeads using Interdigitated Electrodes Array
Author :
Zou, Zhiwei ; Lee, Soo-Hyun ; Ahn, Chong H.
Author_Institution :
Univ. of Cincinnati, Cincinnati
Abstract :
This paper presents a polymer microfluidic biochip integrated with interdigitated electrodes arrays (IDAs), which is used for simultaneous separation, accumulation, and detection of microbeads using dielectrophoresis (DEP) and electrical impedance spectroscopy (EIS) methods. The DEP response of silica microspheres has been characterized, and microspheres with different sizes (1.8 mum and 3.5 mum) have been successfully separated and individually trapped in different microchambers with IDAs. Simultaneously, the impedance variation caused by captured microspheres at IDAs has been analyzed.
Keywords :
arrays; bioMEMS; biological techniques; electrochemical electrodes; electrochemical impedance spectroscopy; electrophoresis; lab-on-a-chip; microfluidics; particle size; polymers; silicon compounds; SiO2; dielectrophoretic separation; electrical impedance spectroscopy methods; interdigitated electrodes array; microbeads accumulation; microbeads impedimetric detection; polymer microfluidic biochip; silica microspheres; size 1.8 mum; size 3.5 mum; Dielectrophoresis; Electrochemical impedance spectroscopy; Electrodes; Fabrication; Frequency; Immune system; Impedance measurement; Microfluidics; Polymers; Silicon compounds; Dielectrophoresis; Impedance Spectroscopy; Interdigitated Electrodes Arrays; Microbeads;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International
Conference_Location :
Lyon
Print_ISBN :
1-4244-0842-3
Electronic_ISBN :
1-4244-0842-3
DOI :
10.1109/SENSOR.2007.4300390
