Title :
Optimization of bipolar and tetrapolar impedance biosensors
Author :
Kassanos, Panagiotis ; Demosthenous, Andreas ; Bayford, Richard H.
Author_Institution :
Dept. of Electron. & Electr. Eng., Univ. Coll. London, London, UK
fDate :
May 30 2010-June 2 2010
Abstract :
Impedance detection plays a crucial role in the development of Lab-on-a-Chip (LOAC) technologies. Various types of impedance biosensors have been developed over the years, with the main focus being centered on interdigital sensors. Optimization of impedance sensors has only recently attracted interest. In this paper we present a conformal mapping approach to the optimization of bipolar and tetrapolar impedance sensors. This technique enables an analytic equation for the sensitivity of the sensors to impedance changes to be obtained. Optimization of these sensors using this analytic equation was performed and a number of optimized sensor designs are presented in this paper.
Keywords :
bioelectric phenomena; biological techniques; electric impedance measurement; electric sensing devices; lab-on-a-chip; microsensors; optimisation; bipolar impedance biosensors; interdigital sensors; lab-on-a-chip technology; optimization; tetrapolar impedance biosensors; Biosensors; Conformal mapping; Current density; Design optimization; Electrodes; Equations; Geometry; Impedance; Lab-on-a-chip; Power system modeling;
Conference_Titel :
Circuits and Systems (ISCAS), Proceedings of 2010 IEEE International Symposium on
Conference_Location :
Paris
Print_ISBN :
978-1-4244-5308-5
Electronic_ISBN :
978-1-4244-5309-2
DOI :
10.1109/ISCAS.2010.5537373
