A Semi-automatic System for Measuring Tibial Cartilage Volume

Osteoarthritis is a chronic and crippling disease affecting an increasing number of people each year. With no known cure, it is expected to reach epidemic proportions in the coming years. Currently, there is strong interest in developing a fully automated cartilage area/volume measurement method in the medical field to assist both pharmaceutical companies and medical professions in researching the disease. This paper describes the development of a semi-automatic system for segmenting and measuring human knee cartilage volume from Magnetic resonance imaging (MRI) scans. The cartilage volume obtained from the semi-automated method has been benchmarked against the current gold standard (cartilage volume from manual segmentation).