Title :
Blood Plasma Separation Device using Capillary Phenomenon
Author :
Khumpuang, S. ; Tanaka, T. ; Aita, F. ; Meng, Z. ; Ooe, K. ; Ikeda, M. ; Omori, Y. ; Miyamura, K. ; Yonezawa, H. ; Matsumoto, K. ; Sugiyama, S.
Author_Institution :
Ritsumeikan Univ., Shiga
Abstract :
A microdevice for blood plasma separation using capillary phenomenon has been proposed in this work. Blood plasma can be separated by microcapillary channels fabricated by silicon bulk- micromachining process. The 2 times 3 cm2 device with 1 mm-thick consists of a silicon separation chip and a glass cover. The separation was relatively fast (less than 2 minutes) after a blood-drop (20 mul) was drawn into the channels until the flow stopped. The device was designed for collecting 1 mul of plasma. Due to the advantages in a small sample volume, no power consumption, made the device possible for a blood diagnosis on a chip which promises the applications in point-of-care testing (POCT).
Keywords :
channel flow; flow separation; haemodynamics; haemorheology; microfluidics; micromachining; blood diagnosis; blood plasma separation device; capillary phenomenon; glass cover; microcapillary channels; point-of-care testing; silicon bulk-micromachining process; silicon separation chip; Blood; Cells (biology); Microfluidics; Plasma applications; Plasma chemistry; Plasma devices; Plasma diagnostics; Plasma properties; Reservoirs; Silicon; blood diagnostics; capillary phenomenon; point-of-care; ¿TAS;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International
Conference_Location :
Lyon
Print_ISBN :
1-4244-0842-3
Electronic_ISBN :
1-4244-0842-3
DOI :
10.1109/SENSOR.2007.4300546
