Title :
MEMS-based blood cell counting system
Author :
Piacentini, Niccolò ; Demarchi, Danilo ; Civera, Pierluigi ; Knaflitz, Marco
Author_Institution :
Dept. of Electron., Politec. di Torino, Turino
fDate :
Aug. 31 2008-Sept. 3 2008
Abstract :
Here we present a biomedical system for blood cell counting, based on micro-electro-mechanical-systems (MEMS) technology, designed and realized to obtain portability and low consumptions. The system consists of an assembly of three distinct parts: a micro electro-fluidic lab-on-a-chip (LOC), a mechanical-fluidic interface (MFI) and an electronic board (EB). LOC, realized in two versions, features a novel kind of parallel, multiple channel Coulter cell counter. MFI consists of a plastic holder for fluidic coupling and electrical connection to an EB, hosting all the electronics for cell counting. Preliminary experiments achieved proper fluidic working (absence of clogging, electrode stability, watertight coupling) and the proof-of-concept for combined electro-optical counting.
Keywords :
bioMEMS; biomedical measurement; blood; cellular biophysics; electro-optical effects; lab-on-a-chip; microfluidics; MEMS blood cell counting system; biomedical system; electrode stability; electronic board; electrooptical counting; mechanical-fluidic interface; microelectro-mechanical-systems technology; microelectrofluidic lab-on-a-chip; parallel multiple channel Coulter cell counter; plastic holder; watertight coupling; Assembly systems; Blood; Cells (biology); Counting circuits; Couplings; Electrodes; Lab-on-a-chip; Micromechanical devices; Plastics; Stability;
Conference_Titel :
Electronics, Circuits and Systems, 2008. ICECS 2008. 15th IEEE International Conference on
Conference_Location :
St. Julien´s
Print_ISBN :
978-1-4244-2181-7
Electronic_ISBN :
978-1-4244-2182-4
DOI :
10.1109/ICECS.2008.4674825