Portable biomarker detection with magnetic nanotags

Author

Hall, Drew A. ; Wang, Shan X. ; Murmann, Boris ; Gaster, Richard S.

Author_Institution

Dept. of Electr. Eng., Stanford Univ., Stanford, CA, USA

fYear

2010

fDate

May 30 2010-June 2 2010

Firstpage

1779

Lastpage

1782

Abstract

This paper presents a hand-held, portable biosensor platform for quantitative biomarker measurement. By combining magnetic nanoparticle (MNP) tags with giant magnetoresistive (GMR) spin-valve sensors, the hand-held platform achieves highly sensitive (picomolar) and specific biomarker detection in less than 20 minutes. The rapid analysis and potential low cost make this technology ideal for point-of-care (POC) diagnostics. Furthermore, this platform is able to detect multiple biomarkers simultaneously in a single assay, creating a promising diagnostic tool for a vast number of applications.

Keywords

biosensors; giant magnetoresistance; microprocessor chips; nanoelectronics; nanoparticles; giant magnetoresistive spin valve sensor; hand held biosensor; magnetic nanoparticle tag; multiple portable biomarker detection; point-of-care diagnostic; portable biosensor; quantitative biomarker measurement; Biomarkers; Biosensors; Costs; Fluorescence; Giant magnetoresistance; Immune system; Light emitting diodes; Magnetic analysis; Magnetic sensors; Personal digital assistants;

fLanguage

English

Publisher

ieee

Conference_Titel

Circuits and Systems (ISCAS), Proceedings of 2010 IEEE International Symposium on

Conference_Location

Paris

Print_ISBN

978-1-4244-5308-5

Electronic_ISBN

978-1-4244-5309-2

Type

conf

DOI

10.1109/ISCAS.2010.5537639

Filename

5537639