Nonstationary fluctuations of arterial pressure in sino-aortic deafferented rats

Author

Pan, Shaugun ; Myers, Glenn ; Jacobs, Howard ; Lewis, Stephen ; Brody, Michael J.

Author_Institution

Iowa Univ., IA, USA

fYear

1988

fDate

4-7 Nov. 1988

Firstpage

135

Abstract

Sinaortic deafferented (SAD) rats, in which the baroreflex is removed, exhibit increased fluctuations in arterial pressure (AP) compared to sham-operated (SHM) rats. The power spectrum of AP variability is estimated using the method of averaged periodograms. The relatively short interval over which the AP time series is stationary prevents resolution of spectral components below 1 Hz by this method. An autoregressive (AR) model is used, allowing resolution of spectral peaks at frequencies below 1 Hz. Choice of model order was guided by the Akaike information criterion. A peak at 0.4 Hz was found in the SHM but not the SAD rats, suggesting that it may represent oscillations associated with neural and/or humoral component of the baroflex. A smaller peak near 2 Hz is thought to represent respiratory influences on AP.<>

Keywords

haemodynamics; neurophysiology; signal processing; AP; AR model; Akaike information criterion; SAD rats; SHM rats; arterial pressure; autoregressive model; baroreflex; humoral baroflex; neural baroflex; sham-operated rats; sino-aortic deafferented rats; spectral resolution;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE

Conference_Location

New Orleans, LA, USA

Print_ISBN

0-7803-0785-2

Type

conf

DOI

10.1109/IEMBS.1988.94443

Filename

94443