A model-based approach for the quantification of H reflex depression in humans

Author

Kohn, Andre F. ; Floeter, Mary Kay ; Hallett, Mark

Author_Institution

NIH, NINDS, Bethesda, MD, USA

Volume

2

fYear

1995

fDate

20-23 Sep 1995

Firstpage

1233

Abstract

The analysis of the H reflex, a homologue of the stretch reflex, is useful as an aid in understanding certain neurologic disorders as it reflects some aspects of spinal cord neuronal circuitry and dynamics. Here, a dynamical model is used to describe the H reflex depression in humans in response to trains of stimuli. The model describes the interplay of neurotransmitter depletion and replenishment in the presynaptic boutons and has been used to study transmitter turnover in the Ia to motoneuron synapses in the cat

Keywords

neurophysiology; physiological models; H reflex depression; H reflex depression quantification; Ia to motoneuron synapses; cat; dynamical model; humans; model-based approach; neurologic disorders; neuronal dynamics; neurotransmitter depletion; neurotransmitter replenishment; presynaptic boutons; spinal cord neuronal circuitry; stimuli trains; stretch reflex homologue; Algebra; Circuits; Electrodes; Equations; Humans; Muscles; Neurotransmitters; Spinal cord; Steady-state; Tendons;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference

Conference_Location

Montreal, Que.

Print_ISBN

0-7803-2475-7

Type

conf

DOI

10.1109/IEMBS.1995.579657

Filename

579657