Title :
A model-based approach for the quantification of H reflex depression in humans
Author :
Kohn, Andre F. ; Floeter, Mary Kay ; Hallett, Mark
Author_Institution :
NIH, NINDS, Bethesda, MD, USA
Abstract :
The analysis of the H reflex, a homologue of the stretch reflex, is useful as an aid in understanding certain neurologic disorders as it reflects some aspects of spinal cord neuronal circuitry and dynamics. Here, a dynamical model is used to describe the H reflex depression in humans in response to trains of stimuli. The model describes the interplay of neurotransmitter depletion and replenishment in the presynaptic boutons and has been used to study transmitter turnover in the Ia to motoneuron synapses in the cat
Keywords :
neurophysiology; physiological models; H reflex depression; H reflex depression quantification; Ia to motoneuron synapses; cat; dynamical model; humans; model-based approach; neurologic disorders; neuronal dynamics; neurotransmitter depletion; neurotransmitter replenishment; presynaptic boutons; spinal cord neuronal circuitry; stimuli trains; stretch reflex homologue; Algebra; Circuits; Electrodes; Equations; Humans; Muscles; Neurotransmitters; Spinal cord; Steady-state; Tendons;
Conference_Titel :
Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-2475-7
DOI :
10.1109/IEMBS.1995.579657
