Title :
The effect of transverse tubular sodium channels on action potentials and membrane currents in skeletal muscle
Author :
Henneberg, Kaj-Åge
Author_Institution :
Inst. de Genie Biomed., Montreal Univ., Que., Canada
Abstract :
Computer simulations are used to study the effect of transverse tubular sodium channels on sarcolemmal and tubular action potential propagation in skeletal muscle. The results show that only a very small fraction of the tubular sodium channels are likely to open during an action potential
Keywords :
bioelectric phenomena; biology computing; biomembrane transport; digital simulation; muscle; physiological models; sodium; Na; channel opening; computer simulations; membrane currents; sarcolemmal action potential propagation; skeletal muscle; transverse tubular sodium channels effect; tubular action potential propagation; Biomembranes; Clamps; Computational modeling; Computer simulation; Kinetic theory; Leakage current; Muscles; Optical fiber cables; Surface resistance; Voltage;
Conference_Titel :
Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-2475-7
DOI :
10.1109/IEMBS.1995.579794
