Title :
The effects of cardiac assist device on cardiac function recovery during left ventricular regional ischemia
Author :
Zhou, Xiaoqiang ; Bai, Jing
Author_Institution :
Dept. of Electr. Eng., Tsinghua Univ., Beijing, China
Abstract :
A two-compartment model of the left ventricle (LV) consists of normal myocardium and ischemic myocardium has been established and incorporated into the multi-element cardiovascular model developed based on Barnea´s work (1990). In computer simulation, cardiac function (cardiac output as an indicator) recovery has been investigated under two conditions: with and without Intraaortic balloon pumping (IABP). The simulation results indicate that during serious ischemia, the normal myocardium has no ability to return the cardiac function to pre-ischemic level because of the limit of energy reserve in this region. However, when IABP is used, the energy reserve can be augmented and cardiac function can be restored
Keywords :
artificial organs; cardiology; digital simulation; haemodynamics; physiological models; cardiac assist device effects; cardiac function recovery; energy reserve limit; intraaortic balloon pumping; ischemic myocardium; left ventricular regional ischemia; multielement cardiovascular model; normal myocardium; serious ischemia; two-compartment model; Cardiology; Cardiovascular system; Computational modeling; Computer simulation; Equations; Heart; Ischemic pain; Myocardium; Time varying systems; Veins;
Conference_Titel :
Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-2475-7
DOI :
10.1109/IEMBS.1995.579806
