Title :
A lung disease model to predict the efficacy of inhaled nitric oxide therapy
Author :
Moon, Jon K. ; Gomez, Michael R. ; Hansen, Thomas N.
Author_Institution :
Dept. of Pediatrics, Baylor Coll. of Med., Houston, TX, USA
Abstract :
Inhaled nitric oxide (INO) therapy was evaluated with a model of neonatal lung disease. INO was effective in treatment of primary pulmonary hypertension at doses of 20 and 80 ppm. Severe parenchymal lung disease would respond if 20 ppm INO could eliminate pulmonary shunts. INO may be ineffective for less severe disease compared to oxygen support
Keywords :
lung; nitrogen compounds; patient treatment; physiological models; NO; inhaled nitric oxide therapy efficacy prediction; lung disease model; neonatal lung disease; oxygen support; primary pulmonary hypertension treatment; pulmonary shunts; severe parenchymal lung disease; Biomembranes; Blood; Diseases; Lungs; Medical treatment; Pediatrics; Predictive models; Testing; Veins; Ventilation;
Conference_Titel :
Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-2475-7
DOI :
10.1109/IEMBS.1995.579812
