Title :
Fibrinolytic process in static magnetic fields
Author :
Iwasaka, Masakazu ; Ueno, Shoogo ; Tsuda, Hiroko
Author_Institution :
Fac. of Med., Tokyo Univ., Japan
Abstract :
The authors investigated the effects of magnetic fields on the fibrinolytic process. Dissolution of fibrin polymers by plasmin under a static, and homogeneous magnetic field at 7.84 T was investigated using two methods. In order to avoid the effect of gradient magnetic fields, one ml of fibrin clots in tubes were used to observe the fibrinolysis in a homogeneous magnetic field at 7.84 T. The authors observed no effect of a homogeneous magnetic field at 7.84 T on the dissolution of a fibrin. Results of the turbidity measurement of fibrin gels also show that a homogeneous magnetic field at 7.84 T did not affect fibrinolysis. On the other hand, the authors observed significant enhancement in fibrinolysis when gradient magnetic fields (B·dB/dz=350-400 T2/m) were applied to the fibrinolytic process in the fibrin column
Keywords :
biological effects of fields; biomagnetism; biomolecular effects of radiation; blood; gels; magnetic field effects; proteins; turbidity; 7.84 T; fibrin clots; fibrin column; fibrin gels; fibrin polymers dissolution; fibrinolytic process; gradient magnetic fields; homogeneous magnetic field; static magnetic fields; turbidity measurement; Blood; Boring; Coagulation; Hospitals; Laboratories; Magnetic field measurement; Magnetic fields; Magnetic materials; Polymers; Superconducting magnets;
Conference_Titel :
Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-2475-7
DOI :
10.1109/IEMBS.1995.579917