VLSI-enabled DNA sequencing arrays

Author

Singh, Rajiv Ranjan ; Manickam, Arun ; Ayazian, S. ; Hassibi, Arjang ; Shahrjerdi, Davood

Author_Institution

Electr. & Comput. Eng. Dept., Univ. of Texas at Austin, Austin, TX, USA

fYear

2011

fDate

7-10 Aug. 2011

Firstpage

1

Lastpage

4

Abstract

Massively-parallel, integrated, sensitive and low-cost bio-molecular detectors are an essential part of “next generation” DNA sequencing systems. This paper discusses various design methodologies that leverage the versatility of VLSI technologies, specifically CMOS fabrication processes, to build highly integrated sequencing arrays while addressing the stringent detection and integration requirements. The goal of this paper is to discuss both the advantages and the limitations of next generation VLSI-enabled DNA sequencers.

Keywords

CMOS integrated circuits; VLSI; biomolecular electronics; biosensors; integrated circuit design; lab-on-a-chip; CMOS fabrication process; VLSI-enabled DNA sequencing array; biomolecular detector; design methodology; next generation DNA sequencing system; next generation VLSI-enabled DNA sequencer; Arrays; Bioinformatics; Genomics; Multiplexing; Optical device fabrication; Optical sensors; Polymers;

fLanguage

English

Publisher

ieee

Conference_Titel

Circuits and Systems (MWSCAS), 2011 IEEE 54th International Midwest Symposium on

Conference_Location

Seoul

ISSN

1548-3746

Print_ISBN

978-1-61284-856-3

Electronic_ISBN

1548-3746

Type

conf

DOI

10.1109/MWSCAS.2011.6026444

Filename

6026444