Title :
Development of non-invasive breath analyzer : A proposed system for detection of Nitric oxide (NO) in exhaled human breath, using infrared Quantum Cascade Laser (QCL) absorption technique
Author :
Arekar, S. ; Daruwala, R.D.
Author_Institution :
Electr. & Electron. Eng. Dept., VJTI, Mumbai, India
Abstract :
The detection and monitoring of gases in exhaled human breath till date has been limited by the lack of appropriate materials and technologies which could rapidly and selectively identify the presence and monitor the concentration of trace levels of specific biomarkers. In this paper, a method for detection of NO in exhaled breath has been proposed. Development of a continuous wave, thermoelectrically cooled, Distributed Feedback Quantum Cascade Laser (DFB-QCL) based sensor platform operating near 5.26 μm, in combination with QEPAS has been proposed for the quantitative detection of exhaled NO concentrations, which is a biomarker of airway inflammation and can indicate the extent of respiratory diseases.
Keywords :
biochemistry; biomedical equipment; diseases; distributed feedback lasers; gas sensors; laser applications in medicine; optical sensors; patient monitoring; pneumodynamics; quantum cascade lasers; DFB-QCL based sensor; NO; QEPAS; airway inflammation; biomarker; distributed feedback quantum cascade laser-based sensor; exhaled NO concentrations; exhaled human breath; gas monitoring; infrared quantum cascade laser absorption technique; nitric oxide gas detection; noninvasive breath analyzer; respiratory diseases; thermoelectrical cooling; trace level concentration; Absorption; Biomarkers; Computer architecture; Data acquisition; Diseases; Monitoring; Quantum cascade lasers; Breath analysis; Quartz enhanced Photo acoustic spectroscopy; distributed feedback quantum cascade laser; trace gas nitric oxide detection;
Conference_Titel :
Nascent Technologies in the Engineering Field (ICNTE), 2015 International Conference on
Conference_Location :
Navi Mumbai
Print_ISBN :
978-1-4799-7261-6
DOI :
10.1109/ICNTE.2015.7029941
