Title :
Evidence for origin of basal cell carcinomas in solar (actinic) keratoses
Author :
Lambert, W. Clark
Author_Institution :
Dept. of Pathol., Univ. of Med. & Dentistry of New Jersey, Newark, NJ, USA
Abstract :
The author examined a series of skin biopsy specimens which meet the following criteria: (1) both nonlesional epidermis and epidermis replaced by solar (actinic) keratosis were present on the histopathological slide; (2) in addition to the solar keratosis, a basal cell carcinoma was present on the slide; (3) at least a portion of the basal cell carcinoma was in direct contact with the epidermis. Morphometric analysis of the extent of association of the basal cell carcinomas in contact with the normal epidermis versus with the solar keratoses showed a nonrandom (p<0.1) association with the latter.<>
Keywords :
biomedical measurement; cellular biophysics; skin; statistical analysis; actinic keratoses; basal cell carcinomas; epidermis; morphometric analysis; skin biopsy; solar keratosis;
Conference_Titel :
Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE
Conference_Location :
New Orleans, LA, USA
Print_ISBN :
0-7803-0785-2
DOI :
10.1109/IEMBS.1988.94528
