Title :
Computational methods for predicting intramolecular G-quadruplexes in nucleotide sequences
Author :
D´Antonio, Lawrence ; Bagga, Paramjeet
Author_Institution :
Dept. of Comput. Sci., Ramapo Coll. of New Jersey, Mahwah, NJ, USA
Abstract :
Guanine-rich sequences, including those that form G-quadruplexes, are abundant in regions of biological significance. In order to map putative G-quadruplex elements within mammalian genes we have created a suite of computational tools. This suite contains algorithms to search genes for occurrences of the G-quadruplex motif and determine their distribution near RNA processing sites.
Keywords :
biology computing; genetics; macromolecules; molecular biophysics; RNA processing sites; computational methods; guanine-rich sequences; intramolecular G-quadruplexes prediction; mammalian genes; nucleotide sequences; Bioinformatics; Biology computing; Chemical elements; Chemistry; Computer science; Educational institutions; Proteins; RNA; Stability;
Conference_Titel :
Computational Systems Bioinformatics Conference, 2004. CSB 2004. Proceedings. 2004 IEEE
Print_ISBN :
0-7695-2194-0
DOI :
10.1109/CSB.2004.1332508
