Title :
Comparing 3-D protein structures similarity by using fractal features
Author :
Cui, Chenyang ; Wang, Donghui ; Shi, Jiaoying
Author_Institution :
State Key Lab. of CADandCG, Zhejiang Univ., Hangzhou, China
Abstract :
We propose a new method for finding similarity in 3-D protein structure comparison. Different from the other existing methods, our method is grounded in the theory of fractal geometry. The proposed feature vectors of protein structures are simple to implement. The method is very fast because it requires neither alignment of the chains nor any chain-chain comparison. We calculate the fractal features of a set of 200 protein structures selected from PDB(Protein Data Bank). The experimental result shows that our method is very effective in classification of 3-D protein structures.
Keywords :
biology computing; feature extraction; fractals; molecular biophysics; proteins; 3-D protein structure classification; 3-D protein structures similarity; Protein Data Bank; feature vectors; fractal features; fractal geometry; Amino acids; Computer science; Crystallography; Educational institutions; Feature extraction; Fractals; Geometry; Nuclear magnetic resonance; Proteins; Spatial databases;
Conference_Titel :
Computational Systems Bioinformatics Conference, 2004. CSB 2004. Proceedings. 2004 IEEE
Print_ISBN :
0-7695-2194-0
DOI :
10.1109/CSB.2004.1332549