Title :
A fully electronic DNA sensor with 128 positions and in-pixel A/D conversion
Author :
Schienle, Meinrad ; Frey, A. ; Hofmann, F. ; Holzapfl, B. ; Paulus, C. ; Schindler-Bauer, P. ; Thewes, Roland
Author_Institution :
Infineon Technol., Munich, Germany
Abstract :
A 16x8 CMOS sensor array for fully electronic DNA detection is presented. Each position contains a complete A/D converter with a dynamic range of five decades. The 3σ-homogeneity of the electrical response of the sensor array is better than 6% (10-21A to 10-7A). The 28.8mm2 IC is fabricated in a 0.5μm 2M CMOS process extended to form Au sensors.
Keywords :
CMOS integrated circuits; DNA; analogue-digital conversion; biosensors; electrochemical sensors; CMOS sensor array; DNA sensor array chips; biological functionality; comparator circuits; dynamic range; electrochemical detection; fully electronic DNA sensor; in-pixel A/D conversion; redox-cycling based detection; transducer-generated currents; Capacitors; Circuit testing; Counting circuits; Current measurement; DNA; Electrodes; Gold; Optical sensors; Sensor arrays; Voltage control;
Conference_Titel :
Solid-State Circuits Conference, 2004. Digest of Technical Papers. ISSCC. 2004 IEEE International
Print_ISBN :
0-7803-8267-6
DOI :
10.1109/ISSCC.2004.1332673
