Title :
A 0.18μm CMOS 10-6 lux bioluminescence detection system-on-chip
Author :
Eltoukhy, H. ; Salama, Khaled ; El Gamal, Abbas ; Ronaghi, M. ; Davis, Ronald W.
Author_Institution :
Stanford Univ., CA, USA
Abstract :
A chip comprising a 8x16 pseudo-differential pixel array, 128-channel 13b ADC and column-level DSP is fabricated in a 0.18μm CMOS process. Detection of 10-6lux at 30s integration time is achieved via on-chip background subtraction, correlated multiple sampling and averaged 128 13b digitizations/readout. The IC is 25mm2 and contains 492k transistors.
Keywords :
CMOS image sensors; analogue-digital conversion; bioluminescence; biosensors; differential amplifiers; system-on-chip; ADC; CMOS process; PMOS follower circuit; SIMD array; VGA; bioluminescence detection system-on-chip; column-level DSP; correlated multiple sampling; differential comparator; fully differential amplifier; miniaturized low cost systems; on-chip background subtraction; pseudo-differential pixel array; Bioluminescence; Chemical technology; Circuit noise; Linearity; Luminescence; Pathogens; Photodiodes; Proteins; Shift registers; System-on-a-chip;
Conference_Titel :
Solid-State Circuits Conference, 2004. Digest of Technical Papers. ISSCC. 2004 IEEE International
Print_ISBN :
0-7803-8267-6
DOI :
10.1109/ISSCC.2004.1332674
