• DocumentCode
    3429970
  • Title

    Effect of 17 β-estradiol on Ca2+ channel in mouse C2C12 myoblasts

  • Author

    Bing Leng ; Hao-Gang Xue

  • Author_Institution
    Dept. of Orthopedic Surg., Affiliated Hosp. of Beihua Univ., Jilin, China
  • fYear
    2011
  • fDate
    19-22 Aug. 2011
  • Firstpage
    569
  • Lastpage
    571
  • Abstract
    The present study has investigated effect of 17β-estradiol on Ca2+ channel in mouse C2C12 myoblasts. Whole cell Patch-clamp analysis was used to observe the effects of different doses of 17β-estradiol on changes of Ca2+ channel in C2C12 myoblasts. Currents of Ca2+ were recorded in 67% C2C12 myoblasts. Groups of 30 mol · L-1 and 20 mol L-1 increased currents of Ca2+ significiantly (P<;0.05). While group of 10 mol · L-1 did not change. The present results revealed that 17β-estradiol may regulate C2C12 myoblasts by opening Ca2+ channel in myoblast cell line C2C12.
  • Keywords
    biological techniques; calcium; cellular biophysics; organic compounds; 17β-estradiol effect; Ca2+channel; mouse C2C12 myoblasts; myoblast cell line C2C12; whole cell patch-clamp analysis; Bones; Calcium; Clamps; Humans; Mice; Muscles; Osteoporosis; 17β-estraawl; C2C12 myoblasts; Ca2+ channel;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Human Health and Biomedical Engineering (HHBE), 2011 International Conference on
  • Conference_Location
    Jilin
  • Print_ISBN
    978-1-61284-723-8
  • Type

    conf

  • DOI
    10.1109/HHBE.2011.6028375
  • Filename
    6028375
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3429970