Effect of passive smoking on NO, GSH-pox, NOS, SOD, MDA in serum and lung homogenate of rats

Author

Jiang Yanxia ; Lv Shi-jie ; Xu Junjie ; Lu Xiaojing ; Lei Juntao

Author_Institution

Biochem. Dept., JiLin Med. Coll., Jilin, China

fYear

2011

fDate

19-22 Aug. 2011

Firstpage

680

Lastpage

683

Abstract

This paper researched effect of passive smoking on growth rats. 30 male wistar rats were randomly devided control group(CG), low dose passive smoking group (LDG)and high dose passive smoking group(HDG), LDG and HDG breathed in smoke of three and six cigarettes respectively, twice every day, one time was one hour, altogether was 35 days. Body weight of LDG and HDG was significantly lower than CG (P <; 0.05). NO and MDA in HDG had significant difference to CG in serum and lung homogenate(P <; 0.05), GSH-pox in LDG was obviously lower than CG in serum and lung homogenate(P <; 0.05), NOS and SOD in HDG decreased significantly to LDG and CG in lung homogenate (P <; 0.05). Passive smoking may lead rats growing decreased, perhaps passive smoking made rats oxidation environment change.

Keywords

biochemistry; cellular biophysics; lung; nitrogen compounds; organic compounds; pneumodynamics; smoke; NO; body weight; cigarette smoke; glutathion peroxidase; lung homogenate; malonaldehyde; nitric oxide; nitricoxide synthase; oxidation; passive smoking; rat growth; serum; superoxide dismutase; Biochemistry; Blood pressure; Diseases; Lead; Lipidomics; Lungs; Rats; GSH-pox; MDA; NO; NOS; SOD; passivesmoking;

fLanguage

English

Publisher

ieee

Conference_Titel

Human Health and Biomedical Engineering (HHBE), 2011 International Conference on

Conference_Location

Jilin

Print_ISBN

978-1-61284-723-8

Type

conf

DOI

10.1109/HHBE.2011.6028510

Filename

6028510