The related study of whitening efficacy of ginseng extract-ginsenoside Rb1

Author

Song Wengang ; Sun Liwei ; Li Yu

Author_Institution

Basic Med. Coll., Beihua Univ., Jilin, China

fYear

2011

fDate

19-22 Aug. 2011

Firstpage

820

Lastpage

822

Abstract

Objective: The effect of ginsenoside Rb1 on in vitro mushroom tyrosinase and the proliferation of B16 melanocyte were studied. Method: The detection of in vitro activity of mushroom tyrosinase; The determination of cell proliferation rate. Result: The inhibition rate of Rb1 samples at different concentrations to in vitro mushroom tyrosinase is obviously lower than arbutin with an inhibition rate between ±0.05. The effect of ginsenoside Rb1 on the proliferation of B16 melanocyte is changed along with the changes of concentration. Conclusion: There is no obviously effect of ginsenoside Rb1 on in vitro activity of mushroom tyrosinase. When the concentration is lower than 125 μg/ml, the proliferation of B16 melanocyte is promoted. But the proliferation of B16 melanocyte is depressed with the concentration of ginsenoside Rb1 above 125 μg/ml.

Keywords

biochemistry; cellular biophysics; enzymes; molecular biophysics; organic compounds; pigments; B16 melanocyte proliferation; arbutin; ginseng extract; ginsenoside Rb1; mushroom tyrosinase in vitro activity; whitening efficacy; Biochemistry; Educational institutions; In vitro; Instruments; Lungs; Materials; Ginsenoside Rbl; Melanocyte; Tyrosinase; Whitening;

fLanguage

English

Publisher

ieee

Conference_Titel

Human Health and Biomedical Engineering (HHBE), 2011 International Conference on

Conference_Location

Jilin

Print_ISBN

978-1-61284-723-8

Type

conf

DOI

10.1109/HHBE.2011.6028953

Filename

6028953