Title :
Evaluation of the blood and genetic compatibility of coronary artery stents
Author :
Wen Liu ; Qingfang Liu ; Guochong Chen
Author_Institution :
Sch. of Radiat. Med. & Public Health, Soochow Univ., Suzhou, China
Abstract :
The aim of our study was to evaluate the blood and genetic compatibility of coronary artery stents. We investigated blood compatibility of the sample products by some tests including platelet aggregation test, platelet counts, The Thromboxane B2 concertration, determination of thrombin time, prothrombin time, activated partial throboplastin time and fibrinogen concertration after the samples were inserted into the common carotid artery of a rabbit; genetic compatibility was evaluated by using three in vitro tests that are Ames test, micronucleus test, as well as chromosome aberration test. The results of the these tests preliminarily showed that the coronary artery stents were biocompatible, laying a foundation for further studies and applications of the coronary artery stent.
Keywords :
biomedical measurement; blood; blood vessels; genetics; molecular biophysics; stents; Ames test; activated partial throboplastin time; blood compatibility evaluation; chromosome aberration test; common carotid artery; coronary artery stents; fibrinogen concertration; genetic compatibility evaluation; micronucleus test; platelet aggregation test; platelet counts; prothrombin time; thromboxane B2 concertration; Arteries; Biological cells; Blood; Educational institutions; Genetics; Materials; Rabbits; blood compatibility; coronary artery stent; genetic compatibilit;
Conference_Titel :
Human Health and Biomedical Engineering (HHBE), 2011 International Conference on
Conference_Location :
Jilin
Print_ISBN :
978-1-61284-723-8
DOI :
10.1109/HHBE.2011.6029016
