Evaluation of the blood and genetic compatibility of coronary artery stents

Author

Wen Liu ; Qingfang Liu ; Guochong Chen

Author_Institution

Sch. of Radiat. Med. & Public Health, Soochow Univ., Suzhou, China

fYear

2011

fDate

19-22 Aug. 2011

Firstpage

1100

Lastpage

1103

Abstract

The aim of our study was to evaluate the blood and genetic compatibility of coronary artery stents. We investigated blood compatibility of the sample products by some tests including platelet aggregation test, platelet counts, The Thromboxane B2 concertration, determination of thrombin time, prothrombin time, activated partial throboplastin time and fibrinogen concertration after the samples were inserted into the common carotid artery of a rabbit; genetic compatibility was evaluated by using three in vitro tests that are Ames test, micronucleus test, as well as chromosome aberration test. The results of the these tests preliminarily showed that the coronary artery stents were biocompatible, laying a foundation for further studies and applications of the coronary artery stent.

Keywords

biomedical measurement; blood; blood vessels; genetics; molecular biophysics; stents; Ames test; activated partial throboplastin time; blood compatibility evaluation; chromosome aberration test; common carotid artery; coronary artery stents; fibrinogen concertration; genetic compatibility evaluation; micronucleus test; platelet aggregation test; platelet counts; prothrombin time; thromboxane B2 concertration; Arteries; Biological cells; Blood; Educational institutions; Genetics; Materials; Rabbits; blood compatibility; coronary artery stent; genetic compatibilit;

fLanguage

English

Publisher

ieee

Conference_Titel

Human Health and Biomedical Engineering (HHBE), 2011 International Conference on

Conference_Location

Jilin

Print_ISBN

978-1-61284-723-8

Type

conf

DOI

10.1109/HHBE.2011.6029016

Filename

6029016