DocumentCode
3440462
Title
Matching an oscillator model to a phase response curve
Author
Sacré, Pierre ; Sepulchre, Rodolphe
Author_Institution
Dept. of Electr. Eng. & Comput. Sci. (B28), Univ. of Liege, Liege, Belgium
fYear
2011
fDate
12-15 Dec. 2011
Firstpage
3909
Lastpage
3914
Abstract
The Phase Response Curve (PRC) has proven a useful tool for the reduction of complex oscillator models. It is also an information often experimentally available to the biologist. This paper introduces a numerical tool based on the sensitivity analysis of the PRC to adapt initial model parameters in order to match a particular PRC shape. We illustrate the approach on a simple biochemical model of circadian oscillator.
Keywords
biology; oscillators; PRC; biochemical model; circadian oscillator; complex oscillator models; initial model parameters; numerical tool; phase response curve; sensitivity analysis; Adaptation models; Biological system modeling; Orbits; Oscillators; Sensitivity analysis; Space vehicles;
fLanguage
English
Publisher
ieee
Conference_Titel
Decision and Control and European Control Conference (CDC-ECC), 2011 50th IEEE Conference on
Conference_Location
Orlando, FL
ISSN
0743-1546
Print_ISBN
978-1-61284-800-6
Electronic_ISBN
0743-1546
Type
conf
DOI
10.1109/CDC.2011.6161168
Filename
6161168
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