Two-layer frequency domain property measurements - experiment and hybrid model

Author

Busch, D.R. ; Faris, G.W. ; Alexandrakis, G. ; Patterson, M.S.

Author_Institution

Molecular Phys. Lab., SRI Int., Menlo Park, CA, USA

fYear

2001

fDate

11-11 May 2001

Firstpage

401

Abstract

Summary form only given. Measurement of the optical properties of human tissue is useful for noninvasive monitoring of hemoglobin, therapeutic drugs, and other chromophores. A two-layered model such as skin over muscle or skin over fat, while not anatomically complete, may prove adequate for these applications. We apply a hybrid Monte Carlo-diffusion model to recovery of the optical properties and upper layer thickness of tissue phantoms from spatially-resolved frequency domain measurements.

Keywords

Monte Carlo methods; bio-optics; biological techniques; biological tissues; diffusion; skin; chromophores; fat; hemoglobin; human tissue; hybrid Monte Carlo-diffusion model; hybrid model; muscle; optical properties; skin; spatially-resolved frequency domain measurements; therapeutic drugs; tissue phantoms; two-layer frequency domain property; two-layered model; upper layer thickness; Bayesian methods; Biomedical optical imaging; Frequency domain analysis; Frequency measurement; Image reconstruction; Imaging phantoms; Isosurfaces; Optical distortion; Optical scattering; Optimized production technology;

fLanguage

English

Publisher

ieee

Conference_Titel

Lasers and Electro-Optics, 2001. CLEO '01. Technical Digest. Summaries of papers presented at the Conference on

Conference_Location

Baltimore, MD, USA

Print_ISBN

1-55752-662-1

Type

conf

DOI

10.1109/CLEO.2001.947971

Filename

947971