Bioluminescent bioreporter integrated circuit sensors for very low-level chemical detection

Author

Islam, S.K. ; Qu, W. ; Vijayaraghvan, R. ; Terry, S.C. ; Zhang, M. ; Blalock, B. ; Caylor, S. ; Ripp, S. ; Sayler, G.S.

Author_Institution

Dept. of Electr. & Comput. Eng., Tennessee Univ., Knoxville, TN

fYear

2006

fDate

23-26 Oct. 2006

Firstpage

524

Lastpage

527

Abstract

An integrated CMOS microluminometer for detection of very low-level bioluminescence is presented. Signal processing is accomplished with a current-to-frequency converter circuit. Photodiode, integrator, voltage reference circuit and noise are analyzed in detail in this paper. The biosensor chip was fabricated using a standard 0.35mum CMOS process and dissipate 3 mW for 3.3 V power supply. Test results are given to prove the concept

Keywords

CMOS integrated circuits; bioluminescence; biosensors; chemical sensors; convertors; integrating circuits; photodiodes; reference circuits; 0.35 micron; 3 mW; 3.3 V; CMOS process; bioluminescent bioreporter integrated circuit sensors; biosensor chip; current-to-frequency converter circuit; integrated CMOS microluminometer; integrator; photodiode; signal processing; very low-level bioluminescence detection; very low-level chemical detection; voltage reference circuit; Bioluminescence; Biomedical signal processing; Biosensors; CMOS process; Chemical and biological sensors; Chemical sensors; Integrated circuit noise; Photodiodes; Power supplies; Voltage;

fLanguage

English

Publisher

ieee

Conference_Titel

Solid-State and Integrated Circuit Technology, 2006. ICSICT '06. 8th International Conference on

Conference_Location

Shanghai

Print_ISBN

1-4244-0160-7

Electronic_ISBN

1-4244-0161-5

Type

conf

DOI

10.1109/ICSICT.2006.306342

Filename

4098155