• DocumentCode
    346789
  • Title

    Factors affecting chondrocyte phenotype during monolayer expansion

  • Author

    Malaviya, P. ; Yamaoto, S. ; Nerem, R M

  • Author_Institution
    Inst. of Bioeng., Georgia Inst. of Technol., Atlanta, GA, USA
  • Volume
    1
  • fYear
    1999
  • fDate
    1999
  • Abstract
    Primary bovine articular chondrocyte (BAC) monolayers were treated with fluid shear (0.5 Pa) and hypoxia (5% O2) and compared with monolayers grown under static normoxic conditions. Results indicate that shear stress and hypoxia reverse chondrocyte dedifferentiation observed under static normoxic conditions
  • Keywords
    biorheology; cellular biophysics; monolayers; O2; chondrocyte dedifferentiation reversal; chondrocyte phenotype; fluid shear; hypoxia; monolayer expansion; primary bovine articular chondrocyte monolayers; static normoxic conditions; Biomedical engineering; Bioreactors; Bovine; Polymers; Postal services; Protein engineering; RNA; Stress; Tellurium; Tissue engineering;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    [Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
  • Conference_Location
    Atlanta, GA
  • ISSN
    1094-687X
  • Print_ISBN
    0-7803-5674-8
  • Type

    conf

  • DOI
    10.1109/IEMBS.1999.802153
  • Filename
    802153
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=346789