Effects of acute hyperglycemia on in vivo velocity profiles of the left anterior descending coronary artery

Author

Gross, Eric R. ; Hettrick, Douglas A. ; Kersten, Judy R. ; Pagel, Paul S. ; Warltier, David C.

Author_Institution

Dept. of Anesthesiology, Med. Coll. of Wisconsin, Milwaukee, WI, USA

Volume

1

fYear

1999

fDate

1999

Abstract

The shape of the coronary artery velocity profile is an important determinant of local shear and shear stress gradients. In vivo velocity profiles of the left anterior descending coronary artery by Doppler ultrasound show differences in velocity distributions for canines (N=4) during acute hyperglycemia (HG) as compared to baseline (normoglycemia) conditions. Changes in the velocity profile indicate that HG may have a deleterious effect on coronary blood flow characteristics

Keywords

biomedical ultrasonics; blood vessels; cardiovascular system; haemodynamics; pulsatile flow; Doppler ultrasound; acute hyperglycaemia effects; blood glucose level; canines; coronary blood flow characteristics; in vivo velocity profiles; left anterior descending coronary artery; local shear gradients; shear stress gradients; velocity profile shape; Arteries; Blood flow; Coronary arteriosclerosis; Dogs; Helium; Humans; In vivo; Mechanical factors; Stress; Viscosity;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.802263

Filename

802263