Title :
Effects of acute hyperglycemia on in vivo velocity profiles of the left anterior descending coronary artery
Author :
Gross, Eric R. ; Hettrick, Douglas A. ; Kersten, Judy R. ; Pagel, Paul S. ; Warltier, David C.
Author_Institution :
Dept. of Anesthesiology, Med. Coll. of Wisconsin, Milwaukee, WI, USA
Abstract :
The shape of the coronary artery velocity profile is an important determinant of local shear and shear stress gradients. In vivo velocity profiles of the left anterior descending coronary artery by Doppler ultrasound show differences in velocity distributions for canines (N=4) during acute hyperglycemia (HG) as compared to baseline (normoglycemia) conditions. Changes in the velocity profile indicate that HG may have a deleterious effect on coronary blood flow characteristics
Keywords :
biomedical ultrasonics; blood vessels; cardiovascular system; haemodynamics; pulsatile flow; Doppler ultrasound; acute hyperglycaemia effects; blood glucose level; canines; coronary blood flow characteristics; in vivo velocity profiles; left anterior descending coronary artery; local shear gradients; shear stress gradients; velocity profile shape; Arteries; Blood flow; Coronary arteriosclerosis; Dogs; Helium; Humans; In vivo; Mechanical factors; Stress; Viscosity;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802263
