Title :
Effect of intraluminal thrombus on local abdominal aortic aneurysm wall strength
Author :
Wang, D.H.J. ; Schiro, B.J. ; Makaroun, M.S. ; Webster, M.W. ; Vorp, D.A.
Author_Institution :
Dept. of Surg. & Bioeng., Pittsburgh Univ., PA, USA
Abstract :
We have shown that the intraluminal thrombus (ILT) commonly found within abdominal aortic aneurysm (AAA) significantly attenuates diffusion of oxygen to the aortic wall as its thickness increases. We hypothesize that, as a result, the strength of the AAA wall is inversely related to ILT thickness. We tested the strength of 6 pairs of freshly excised AAA wall specimens from 6 different patients. Uniaxial tensile testing revealed that AAA wall adjacent to thin ILT or no ILT is significantly stronger than that adjacent to thick ILT (p=0.03)
Keywords :
biodiffusion; biomechanics; blood vessels; diseases; O2; diffusion; freshly excised abdominal aortic aneurysm wall specimens; intraluminal thrombus; intraluminal thrombus thickness; local abdominal aortic aneurysm wall strength; patients; uniaxial tensile testing; Abdomen; Aneurysm; Bars; Biomedical engineering; Biomedical measurements; Diseases; History; Surgery; Tensile stress; Testing;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802299
