Development of burst high frequency wave source for medical application

Inducing apoptosis in malignant cells and controlling ES cell differentiation using sub-nanosecond high voltage pulses have been investigated. It is important to develop a high-power, high frequency electromagnetic wave focusing system for apoptosis induction in cancer. Nonlinear lumped element transmission lines (NLETL) to generate RF pulses have in recent years gained much attention. Our intention is to establish a cancer treatment system utilizing NLETLs by combining these two research areas. Here, specific characteristics of output waveforms from the device of NLETLs are investigated considering medical application.