Conversion mechanism for biohybrid microsystems: linear motion of magnetically patterned microorganisms to rotary motion of artificial component

Biohybrid systems, which are composed of biological motors of cells and artificial structure are potential candidates for increasing functions of micromechanical systems. We established a conversion mechanism of the linear motion of magnetically patterned microorganisms through a movable component. First, we developed a fabrication process of a movable component in a microchannel decorated with magnetic blocks. Second, cells of Vorticella were patterned around magnetic blocks in a microchannel using a magnetic force. Finally, a movable component was integrated with a cell to convert its motion. Reciprocating linear actuation was converted to the rotational motion through the movable component. Our developed technologies open the possibility of fabricating a wide range of biohybrid systems.