• DocumentCode
    3478895
  • Title

    The array of micro-reactor PCR chips and its control system

  • Author

    Li, Xianming ; Liu, Haifa

  • Author_Institution
    Sch. of Control Sci. & Eng., Shandong Univ., Jinan, China
  • fYear
    2009
  • fDate
    5-7 Aug. 2009
  • Firstpage
    1167
  • Lastpage
    1172
  • Abstract
    A kind of low cost microreactor polymerase chain reaction (PCR) chips is designed in which there are no temperature sensor and heater, and a temperature control system to the array of this kind of chips is developed. The control system is composed of a unitized macroscopic control subsystem and a distributed microcosmic control subsystem. The temperature that PCR chips need is controlled approximately by unitized macroscopic subsystem in which water as heat medium is pumped through a special heat exchanger. An array of miniature heaters corresponding to the array of PCR chips is made in a flexible printed circuit board that provides temperature compensation to every PCR chip. To be composed a cascade control system and using statistical quality control (SPC) method, the temperature of every chip is controlled quickly and accurately by the miniature heaters cooperating together with the heat exchanger.
  • Keywords
    cascade control; compensation; distributed control; heat exchangers; lab-on-a-chip; microreactors; printed circuits; quality control; temperature control; PCR chip array; cascade control system; distributed microcosmic control subsystem; flexible printed circuit board; heat exchanger; heat medium; macroscopic control subsystem; microreactor polymerase chain reaction chip; miniature heater; statistical quality control method; temperature compensation; temperature control system; Control systems; Costs; Distributed control; Flexible printed circuits; Heat pumps; Polymers; Sensor arrays; Temperature control; Temperature sensors; Water heating; Cascade control; Microelectromechanical systems(MEMS); Polymerase chain reaction(PCR); Statistical quality control(SPC);
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Automation and Logistics, 2009. ICAL '09. IEEE International Conference on
  • Conference_Location
    Shenyang
  • Print_ISBN
    978-1-4244-4794-7
  • Electronic_ISBN
    978-1-4244-4795-4
  • Type

    conf

  • DOI
    10.1109/ICAL.2009.5262598
  • Filename
    5262598