The Design of a Nanometer Biosensor and Its Microfluidic Integration

Author

Hao, Wang ; Wenzhen, Sun ; Xiangang, Luo

Author_Institution

Coll. of Mechatron., Univ. of Electro Sci. & Technol. of China, Chengdu

fYear

2008

fDate

21-24 Sept. 2008

Firstpage

625

Lastpage

628

Abstract

A new biosensor structure, characterized by two layers of metal nano-particle, is proposed and fabricated with NSL (Nano-sphere Lithography) process. It improves sensitivity by exciting LSPR (Localized Surface Plasmonic Resonance) interactions between electromagnetic fields in the two layers. A simple microfluidic integration scheme for the sensor is designed for real-time and in-situ detection. As an important part of the scheme, a new microfluidic pumping mechanism is analyzed and verified with a prototype.

Keywords

biosensors; electromagnetic fields; lithography; microfluidics; nanoparticles; nanosensors; electromagnetic fields; localized surface flasmonic resonance; metal nano-particle; microfluidic integration; microfluidic pumping; nanometer biosensor; nanosphere lithography process; Biological materials; Biomedical optical imaging; Biosensors; Lithography; Microfluidics; Optical sensors; Optical surface waves; Plasmons; Resonance; Sensor phenomena and characterization; LSPR (Localized Surface Plasmonic Resonance); biosensor; microfluidics; micropump;

fLanguage

English

Publisher

ieee

Conference_Titel

Robotics, Automation and Mechatronics, 2008 IEEE Conference on

Conference_Location

Chengdu

Print_ISBN

978-1-4244-1675-2

Electronic_ISBN

978-1-4244-1676-9

Type

conf

DOI

10.1109/RAMECH.2008.4681443

Filename

4681443